3,6-Difluoro-2-pyridinecarboxylic acid
3,6-difluoropyridine-2-carboxylic acid
CAS: 851386-45-3
Molecular Formula: C6H3F2NO2
3,6-Difluoro-2-pyridinecarboxylic acid - Names and Identifiers
| Name | 3,6-difluoropyridine-2-carboxylic acid |
| Synonyms | 3,6-difluoropicolinic acid 3,6-Difluoropyridin-2-carboxylic acid 3,6-Difluoro-2-pyridinecarboxylic acid 3,6-difluoropyridine-2-carboxylic acid 3,6-Difluoro Pyridine-2-Carboxylic Acid 3,6-DIFLUORO PYRIDINE-2-CARBOXYLIC ACID 2-Pyridinecarboxylic acid, 3,6-difluoro- |
| CAS | 851386-45-3 |
| InChI | InChI=1/C6H3F2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11) |
3,6-Difluoro-2-pyridinecarboxylic acid - Physico-chemical Properties
| Molecular Formula | C6H3F2NO2 |
| Molar Mass | 159.09 |
| Density | 1.535 |
| Melting Point | 139-141℃ |
| Boling Point | 277℃ |
| Flash Point | 122℃ |
| Vapor Presure | 0.00218mmHg at 25°C |
| pKa | 2.37±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.515 |
3,6-Difluoro-2-pyridinecarboxylic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
3,6-Difluoro-2-pyridinecarboxylic acid - Introduction
3, a kind of organic compound, chemical formula is C6H3F2NO2. It is a white solid with a special smell. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3, acid is a white crystalline solid.
-Solubility: Soluble in water, alcohols and ether solvents, slightly soluble in non-polar solvents such as petroleum ether.
-Melting point: about 120-122°C.
-Stability: It has good stability at room temperature, but should avoid contact with strong oxidants.
Use:
-Chemical intermediates: 3, acid can be used as an important intermediate in organic synthesis and used to synthesize various organic compounds.
-Drug research: The compound has certain application potential in the field of drug research.
Preparation Method:
3. There are many common ways to prepare acid. In one of the methods, aniline reacts with hydrofluoric acid in acetonitrile to generate 3,6-difluoropyridine. Then, 3,6-difluoropyridine was reacted with sodium tert-butoxide and dimethyl sulfoxide in chloroform to yield 3, fluoridine.
Safety Information:
-Irritating to the skin and eyes, you need to pay attention to protective measures when using it to avoid direct contact.
-During operation and storage, avoid contact with oxidants and high temperature conditions to prevent fire and explosion hazards.
-When using this compound, safe operating procedures should be followed to ensure well-ventilated laboratory conditions.
Nature:
-Appearance: 3, acid is a white crystalline solid.
-Solubility: Soluble in water, alcohols and ether solvents, slightly soluble in non-polar solvents such as petroleum ether.
-Melting point: about 120-122°C.
-Stability: It has good stability at room temperature, but should avoid contact with strong oxidants.
Use:
-Chemical intermediates: 3, acid can be used as an important intermediate in organic synthesis and used to synthesize various organic compounds.
-Drug research: The compound has certain application potential in the field of drug research.
Preparation Method:
3. There are many common ways to prepare acid. In one of the methods, aniline reacts with hydrofluoric acid in acetonitrile to generate 3,6-difluoropyridine. Then, 3,6-difluoropyridine was reacted with sodium tert-butoxide and dimethyl sulfoxide in chloroform to yield 3, fluoridine.
Safety Information:
-Irritating to the skin and eyes, you need to pay attention to protective measures when using it to avoid direct contact.
-During operation and storage, avoid contact with oxidants and high temperature conditions to prevent fire and explosion hazards.
-When using this compound, safe operating procedures should be followed to ensure well-ventilated laboratory conditions.
Last Update：2024-04-09 19:05:52
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Product Name: 3,6-Difluoro Pyridine-2-Carboxylic Acid Visit Supplier Webpage Request for quotation
CAS: 851386-45-3
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Email: 3008007409@qq.com
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CAS: 851386-45-3
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